To safeguard the health of all participants, and in agreement with the SMSB Board, we have decided to translate the original MSB 2020 program to a 100% virtual format, with the support of Imavox, a world leader in the field of virtual events with over 20 years of experience.
New dates : 27-30th September, 2020.
Detailed scientific program
YS : Young Scientist Program subject to change in accordance with the availability of some speakers.
| Sunday 27th September 2020 | ||
| SHORT COURSE 10h00 - 12h30 |
Introduction to metabolomics workflow by Coral Barbas and Serge Rudaz |
Facing the complexity of biopharmaceuticals characterisation Davy Guillarme and Yannis François |
| SHORT COURSE 13h00 - 15h30 |
From Validation to Uncertainty: Taking the Best from Regulations in Bioanalysis Jean-Marc Roussel |
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| 15h45 | Opening ceremony Chairs: Pr Myriam Taverna - University Paris Saclay - Chatenay-Malabry, France & Pr Serge Rudaz - University of Geneva - Switzerland |
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| PLENARY LECTURE 16h00 - 16h40 |
The modular proteome and its biological significance Ruedi Aebersold - Department of Biology, Institute of Molecular Systems Biology, ETH Zurich and Faculty of Science, University of Zurich - Zurich, Switzerland |
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| 16h45 - 17h30 | Start-up session | |
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WORKSHOP
17h30 - 17h50 |
Workshop: How to build an open-source capillary electrophoresis? Part 1 | |
| Monday 28th September 2020 | ||
| PLENARY LECTURE 10h30 - 11h10 |
Designing materials for ultrasensitive biosensing  Molly M. Stevens - Department of Materials, Department of Bioengineering and Institute of Biomedical Engineering, Imperial College - London, United Kingdom |
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| 11h15 | CE-MS and advances in instrumentation Chair: Christian Neusüss Aalen University, Aalen, Germany |
Biopharmaceuticals Chair: Davy Guillarme University of Geneva, Geneva, Switzerland |
| 11h20 | KN 01 - Microchip CE: Characterizing Molecules Large-to-Small using Mass Spectrometers Large-to-Small Michael Ramsey Department of Chemistry, University of North Carolina, USA |
KN 02 - In-depth characterization of biopharmaceuticals using micropillar array columns combined with mass spectrometry Koen Sandra Research Institute for Chromatography, Kortrijk, Belgium |
| 11h45 | Quantification of protein adsorption and optimization of separations in CE and CE-MS. Hervé Cottet - Université de Montpellier, Institut des Biomolécules Max Mousseron, UMR CNRS 5247 - Montpellier, France |
Charge variant analysis of monoclonal antibodies by CZE-MS under native conditions. YS - Kendall Johnson - Barnett Institute of Chemical and Biological Analysis, Department of Chemistry and Chemical Biology, Northeastern University - Boston, USA |
| 12h00 | Evaluation of a nanoflow interface based on the triple-tube coaxial sheath-flow sprayer. YS - Sabrina Ferré - Institute of Pharmaceutical Sciences of Western Switzerland, Group of Analytical Pharmaceutical Chemistry - Geneva, Switzerland |
Online mass spectrometry of CE(SDS)-separated proteins by two-dimensional capillary electrophoresis. YS - Jennifer Römer - Aalen University - Germany |
| 12h15 | Profiling nucleotides in low numbers of mammalian cells by sheathless CE-MS in positive ion mode: circumventing corona discharge. Rawi Ramautar - Leiden University, Leiden Academic Center for Drug Research - Leiden, The Netherlands |
The Detection of a reduced monoclonal antibody (mAb) at low ng/ml concentration in biological samples by CE-MS. Karsten Hendriks - Sciex, Capillary Electrophoresis EMEAI |
| 12h30 | Characterization of post-transcriptional RNA modification by capillary electrophoresis - tandem mass spectrometry. YS - Antony Lechner - CNRS – Unistra UMR 7140, Université de Strasbourg, Laboratoire de Spectrométrie de Masse des Interactions et des Systèmes - Strasbourg, France |
Fab-specific peptide functionalized biomaterials for mAbs capture and analysis. Zhengjin Jiang - Jinan University, institute of pharmaceutical analysis - Ganghzou, China |
| 12h50 - 13h30 |  Workshop |
|
| 15h00 - 15h45 |  Seminar |
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| 15h50 | Comprehensive omics Chair: Alexander Ivanov Northeastern University College of Science, Boston, USA |
Pharmaceuticals and drug development Marianne Fillet University of Liege, Liege, Belgium |
| 15h55 | KN 03 - Adventures in Multidimensional Fractionation for Quantitative Proteomics Jarrod Marto Dana-Farber Cancer Institute and Harvard Medical School, Boston, USA |
KN 04 - Quantitative microscale analytical systems to aid in drug development Mike Roper Department of Chemistry & Biochemistry, The Florida State University, Florida,USA |
| 16h20 | Metabolic Trajectories Following Contrasting Diets from Food Provisions: Identifying Robust Biomarkers of Habitual Diet. Philip Britz-Mc Kibbin - Mc Master University,Department of Chemistry and Chemical Biology - Hamilton, Canada |
Direct analysis of glycosylation pattern of intact antibodies in cell supernatant with LC-MS or CE-MS. Lukas Naumann - Faculty of Chemistry - Aalen University - Aalen, Germany |
| 16h35 | Genomics meets glycomics: a comprehensive omics approach for lung cancer biomarker discovery. Andras Guttman - University of Pannonia - Hungary |
The use of capillary electrophoresis in gene therapy product testing. Stephen Lock - University of Pannonia / SCIEX |
| 16h50 | Native capillary electrophoresis top-down mass spectrometry for the characterization of proteoforms and their complexes. YS - Kevin Jooss - Northwestern University, Departments of Chemistry and Molecular Biosciences - Evantson, USA |
Characterization of antigen-adjuvant interactions in vaccines by Taylor dispersion analysis. YS - Camille Malburet - IBMM, Institute of Biomolecules Max Mousseron - University of Montpellier, CNRS, ENSCM - Montpellier, France |
| 17h05 | Computer-assisted LC(CE)-HRMS analysis tools for untargeted analysis: sources of errors and strategies to overcome them. Guillaume Erny - Faculdade de Engenharia da Universidade do Porto - Portugal |
Fast and robust quality assessment of therapeutic monoclonal antibodies using size exclusion chromatography-mass spectrometry. Raya A. Sadighi -Vrije University of Amsterdam, Division of Bio-Analytical Chemistry - Amsterdam, The Netherlands |
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WORKSHOP
17h30 - 17h50
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Workshop: How to build an open-source capillary electrophoresis? Part 2 | |
| 17h45 - 18h15 | Poster session group 1 | |
| 18h15 - 18h45 | Poster session group 2 | |
| 18h45 - 19h15 | Poster session group 3 | |
| 19h15 - 19h45 | Poster session group 4 | |
| Tuesday 29th September 2020 | ||
| 9h00 | Environmental analysis Chair: Pham Hung Viet Vietnam National University, Hanoi, Vietnam |
Bioaffinity chromatography, monoliths and IMERs Chair: Zhengjin Jiang Jinan University, Ganghzou, China |
| 9h05 | KN 05 - HPLC coupled to high resolution mass spectrometry has boosted environmental research Juliane Hollender Department Environmental Chemistry, Federal Institute of Aquatic Science and Technology (EAWAG), Dübendorf, Switzerland |
KN 06 - Chromatographic Imers as Prototypes for Flow-Chemistry Applications Gabriella Massolini Department of Pharmaceutical Sciences, University of Pavia, Italy |
| 9h30 | Closing the Gap: Enrichment-free analysis of anionic persistent and mobile organic compounds in the sub-ppb range in drinking water by Capillary Electrophoresis-High Resolution Mass Spectrometry. Christian Neusüss - Aalen University - Aalen, Germany |
The potential of Porous Polymer Monoliths for sample preparation in capillary electrophoresis: From enrichment phases to microreactors. Thuy Tran - Institut Galien Paris Sud, UMR8612, Protein and Nanotechnology in Analytical Science (PNAS), CNRS, Univ. Paris-Saclay - Châtenay-Malabry, France |
| 9h45 | Parallel coupling of nano-liquid chromatography with microarray bioassays and nanoelectrospray mass spectrometry for untargeted screening of toxic compounds. Kristina Still - Vrije Universiteit, Division of Bioanalytical Chemistry - Amsterdam, The Netherlands |
Ultra-miniaturized weak affinity chromatography for ligand identification of nanodiscs-solubilized G-protein coupled receptors: a new fragment screening approach in FBDD. YS - Andrea Gottardini - Université de Lyon, Institut des Sciences Analytiques - Lyon, France |
| 10h00 | Development of a miniature and air-transportable liquid chromatograph with UV detector: Crude oil characterisation by GPC-UV. Damien Bazin - Chromatotec, R&D service - Saint-Antoine, France |
Affinity Sheathless CE-MS for the selective study of FcRn - Antibody interaction. YS - Christopher Gstoettner - Leiden University Medical Center, Center for Proteomics and Metabolomics - Leiden - The Netherlands |
| 10h20 |  Award Ceremony |
|
| PLENARY LECTURE 10h25 |
Ion mobility and mass spectrometry detection for chip-based separation devices Detlev Belder - Institut für Analytische Chemie, Fakultät für Chemie und Mineralogie, Universität Leipzig, Germany |
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| 11h15 | Food, beverages, nutrition and health Chair: Ana M. García-Campaña University of Granada, Granada, Spain |
Biosensors, instrumentation and applications Chair: Lorena Dieguez International Iberian Nanotechnology Laboratory, Braga, Portugal |
| 11h20 | KN 07 - Tailored micromotors for analyte (bio)sensing in health applications Alberto Escarpa Department of Analytical Chemistry and Chemical Engineering, University of Alcala de Henares, Spain |
KN 08 - Current trends and applications in biosensors Rita Asquini Department of Information Engineering, Electronics and Telecommunications, Sapienza University, Rome, Italy |
| 11h45 | Analysis of nutritional and bioactive compounds in food supplements using purpose-made CE with contactless conductivity detection: a case study in Vietnam. Pham Hung Viet- VNU University of Science, Vietnam National University,VNU Key Laboratory of Analytical Technology for Environmental Quality and Food Safety Control - Hanoi, Vitenam |
Lab on a chip for the electrochemical quantitation and recycling of strategic material. Anne Varenne - Institut of Chemistry for Life and Health Sciences, CNRS 2027, Chimie ParisTech PSL - Paris, France |
| 12h00 | Supercritical fluid chromatography tandem mass spectrometry combined with miniaturized extraction techniques as a promising tool for the analysis of vitamin D metabolites in biological samples. YS - Bárbara Socas Rodríguez - Lund University, Green Technology Group - Lund, Sweden |
Quantification of protein expression locally on tissue sections to evaluate tumor heterogeneity. YS - Anna Fomitcheva Khartchenko - IBM Research, Precision Diagnostics - Zurich, Switzerland |
| 12h15 | Green micro-separation of phenolic acid and flavonoid using 3D printed lab on a chip device. Haider Al Lawati - Sultan Qaboos University, Chemistry - Oman |
Pending |
| 14h40 - 15h10 | Poster session group 1 | |
| 15h10 - 15h40 | Poster session group 2 | |
| 15h40 - 16h10 | Poster session group 3 | |
| 16h10 - 16h40 | Poster session group 4 | |
| 16h45 - 17h30 |  Seminar |
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|
WORKSHOP
17h30 - 17h50
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Workshop: How to build an open-source capillary electrophoresis? Part 3 | |
| 18h00 | Point-of-care devices, innovation in microfluidics, precision medecine Chair: Vince Remcho Oregon State University, Corvallis, USA |
Organ- and cell-on-chip Chair: Stéphanie Descroix Centre de recherche de l'Institut Curie, Paris, France |
| 18h05 | KN 09 - Advanced Tools in Precision Medicine: from 3D in vitro tissue models to point-of-care diagnostics Frederic Zenhausern University of Arizona, Phoenix, USA |
KN 10 - Microscale biochemical assays for multiomic profiling of tumor sections Govind Kaigala IBM Research Laboratory, Zurich, Switzerland |
| 18h30 | Multiplexing Neurochemical Detection with Carbon Electrodes and Fast Scan Cyclic Voltammetry. YS - Alexander Zestos - American University - Washington D.C., USA |
Arrays of micro-magnets for negative selection of Circulating Tumor Cells in a microfluidic device. YS - Lucie Descamps - Université Lyon 1,Institut des Nanotechnologies de Lyon - Lyon, France |
| 18h45 | Concentration and separation of DNA in complex biological fluids with µLAS technology. Audrey Boutonnet-Rodat - ADELIS, R&D department - Labège, France |
Extraction of NSAIDS and their metabolites from liver-on-chip samples by dispersive liquid-liquid microextraction based on the solidification of the floating organic drop. YS - Maarten van der Horst - Hogeschool Leiden, LCAB - Leiden, The Netherlands |
| 19h00 | Capillary flow LC-MS usig micro pillar array columns: Combinig nano flowsensitivity with analytical flow robustness throughput. Paul Jacobs - PharmaFluidics, R&D - Ghent, Belgium |
Fabrication of 2D monolayers and 3D spheroids of cells in acoustic levitation. Nathan Jeger-Madiot - ESCPI / CNRS, PMMH - Paris, France |
| Wednesday 30th September 2020 | ||
| 8h40 | Electrodriven separations - AFSEP Session 1 Chair: Hervé Cottet University of Montpellier, Montpellier, France |
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| 8h45 | CE-ICP/MS and TDA/ICP-MS for the characterization of a therapeutic gadolinium-based nanoparticle. YS - Lucie Labied - Institut des Sciences Analytiques, Techniques Séparatives - Lyon, France |
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| 9h00 | Coupling on-chip HPLC and electrochromatography to ion mobility spectrometry. YS - Nora Hartner - Leipzig University, Institute of Analytical Chemistry - Leipzig, Germany |
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| 9h15 | ROMANCE strikes back: on the path to reliable CE-MS quantification. Santiago Codesido Sanchez - Université de Genève, Analytical Sciences - Geneva, Switzerland |
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| 9h30 | Analysis of lipid-conjugated oligonucleotides by cyclodextrin-modified capillary zone electrophoresis. Fatima Barakat - Bordeaux University, ChemBioPharm team, ARNA INSERM U1212, CNRS 5320 - Bordeaux, France |
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| 9h45 | Ultra-fast chiral separations of biomolecules by voltage-gradient gas-phase electrophoresis. Govert W. Somsen - Division of Bioanalytical Chemistry, Amsterdam Institute for Molecules, Medicines and Systems - Amsterdam, The Netherlands |
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| 10h15 - 10h35 |  Seminar |
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| 10h40 | Miniaturized sample preparation techniques Chair: Hong Heng See University of Technology Malaysia, Johor, Malaysia |
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| 10h45 | Electrodriven separations - AFSEP Session 2 Chair: Yannis Francois University of Strasbourg, Strasbourg, France |
KN 11 - Liquid phase microextraction of biological samples – from principles to automation Pavel Kuban Institute of Analytical Chemistry of the Czech Academy of Sciences, Brno, Czech Republic |
| 10h55 | Capillary electrophoresis tandem mass spectrometry for proteomics in the context of multiple myeloma: investigation of two hyphenating approaches. YS - Marie-Jia Gou - University of Liege, Laboratory for The Analysis of Medicines - Liège, Belgium |
|
| 11h10 | Analysis and investigation of acid-base and electromigration properties of applied and potential peptide drugs by capillary electromigration methods. Vaclav Kasicka - Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Electromigration methods - Prague, Czech Republic |
On-chip sample preparation using a ChipFilter coupled to nanoLC-MS/MS for bottom-up proteomics. Ndiaye Massamba Mbacké - ESPCI Paris, Laboratoire de Spectrométrie de Masse Biologique et Protéomique SMBP - Paris, France |
| 11h25 | Physicochemical protein properties, quality and binding affinities. Hermann Wätzig - Medicinal and Pharmaceutical Chemistry, Technical University - Braunschweig, Germany |
Solid sampling probe based on a polymer inclusion membrane. YS - Hui Yin Tey -University of Technology Malaysia, Centre for Sustainable and Nanomaterials - Johor, Malaysia |
| 11h40 | Metabo-ring study: a multi-center trial for the identification of metabolites in biological samples by CE-MS. YS - Nicolas Drouin - Leiden University, Analytical Biosciences and Metabolomics - Leiden, The Netherlands |
New approach for on-chip magnetic immuno-extraction of exosomes. Monica Araya-Farias -Curie Institute, UMR 168 - Paris, France |
| 11h55 | Selection and application of markers for CE-DAD migration time correction of peptide maps used to assess enzyme activity. Karen Waldron - University of Montreal, Department of Chemistry - Montreal, Canada |
Buffer exchange using bidirectional flow. YS - Vesna Bacheva - IBM Research - Zurich, Suisse Technion - Israel Institute of Technology, Science and Technology department - Haifa, Israël |
| 12h15 - 13h00 |  Seminar |
|
| 14h45 | Portable and purpose-made devices Chair: Peter Hauser University of Basel, Basel, Switzerland |
Biomarkers; clinical, diagnostic and forensic applications Chairs: Frederic Robert - Sebia, Lisses, France Philip Britz-McKibbin - McMaster University, Hamilton, Canada |
| 14h50 | KN 12 - A few contributions to the development of capillary electrophoresis systems Claudimir Lucio do Lago Institute of Chemistry, University of São Paulo, Brasil |
KN 13 - Capillary Electrophoresis application in Forensic Medicine and Science Franco Tagliaro Unit of Forensic Medicine, Department of Diagnostics and Public Health, University of Verona, Verona, Italy |
| 15h15 | A portable CE-LIF prototype system of the Ocean Worlds Life Surveyor (OWLS) instrument suite for potential astrobiology spaceflight missions. Florian Kehl - NASA Jet Propulsion Laboratory, California Institute of Technology Chemical Analysis and Life Detection - Pasadena, USA |
In-depth characterization of glycated and carbamylated hemoglobin in clinical samples by top-down CE-MS/MS. Alexander Stolz - Aalen University - Germany |
| 15h30 | A microfluidic HPLC-droplet-ESI-MS chip for the investigation of enzyme inhibitors. YS - Andrea Peretzki - Leipzig University, Institute of Analytical Chemistry - Leipzig, Germany |
Capillary Isotachophoresis separation of exosomes. Yuliya Shakalisava - Leiden University, Leiden Academic Center for Drug Research - Leiden, The Netherlands |
| 15h45 | Application of Microfluidic Glass-based Interfaces for 2D Electromigrative Separation Techniques. YS - Hannes Graf - Eberhard Karls Universität Tübingen, Institute of Physical and Theoretical Chemistry - Tübingen, Germany |
Deep and highly sensitive CZE-MS-based glycan profiling of human plasma and blood-derived immunoglobulin G and extracellular vesicle isolates. Alexander Ivanov - Northeastern University College of Science, Department of Chemistry and Chemical Biology - Boston, USA |
| 16h00 | A new concept for modular CE with LiF detection: a highlight with O-glycans analysis. YS - Théo Liénard--Mayor - Institut Galien Paris-Sud, PNAS - Chatenay-Malabry, France |
Steroid profile in human seminal fluid: is it linked to sperm quality? YS - Eulalia Olesti - Biomedical and metabolomics analysis, Analytical Sciences, University of Geneva - Geneva, Switzerland |
| PLENARY LECTURE 16h35 - 17h15 |
New developments in metabolomics with CE-MS Coral Barbas - Center for Metabolomics and Bioanalysis (CEMBIO) - Universidad San Pablo CEU - Madrid, Spain |
|
| 17h15 - 17h30 | Awards/Prizes ceremony | |
|
WORKSHOP
17h30 - 17h50
|
Workshop: How to build an open-source capillary electrophoresis? Part 4 | |
| 17h50 - 18h00 | MSB 2021 | |
| 18h00 - 18h15 | Closing ceremony | |