To safeguard the health of all participants, and in agreement with the SMSB Board, we have decided to translate the original MSB 2020 program to a 100% virtual format, with the support of Imavox, a world leader in the field of virtual events with over 20 years of experience.


New dates : 27-30th September, 2020.

Detailed scientific program
    YS : Young Scientist                                                                                      Program subject to change in accordance with the availability of some speakers.

                     Sunday 27th September 2020
     
SHORT COURSE 
10h00 - 12h30
Introduction to metabolomics workflow
by Coral Barbas and Serge Rudaz
Facing the complexity of biopharmaceuticals characterisation
Davy Guillarme and Yannis François
SHORT COURSE 
13h00 - 15h30
From Validation to Uncertainty: Taking the Best from Regulations in Bioanalysis
Jean-Marc Roussel
 
15h45 Opening ceremony
Chairs: Pr Myriam Taverna - University Paris Saclay - Chatenay-Malabry, France
 & Pr Serge Rudaz - University of Geneva - Switzerland
PLENARY
LECTURE

16h00 - 16h40
The modular proteome and its biological significance
Ruedi Aebersold - Department of Biology, Institute of Molecular Systems Biology,
ETH  Zurich and Faculty of Science, University of Zurich - Zurich, Switzerland
16h45 - 17h30 Start-up session
WORKSHOP
17h30 - 17h50
Workshop: How to build an open-source capillary electrophoresis? Part 1
     
                    Monday 28th September 2020
     
PLENARY
LECTURE

10h30 - 11h10
                               Designing materials for ultrasensitive biosensing         
Molly M. Stevens - Department of Materials, Department of Bioengineering
and Institute of Biomedical Engineering, Imperial College - London, United Kingdom
     
11h15 CE-MS and advances in instrumentation
Chair: Christian Neusüss
Aalen University, Aalen, Germany
Biopharmaceuticals
Chair: Davy Guillarme
University of Geneva, Geneva, Switzerland
11h20 KN 01 - Microchip CE: Characterizing Molecules Large-to-Small using Mass Spectrometers Large-to-Small
Michael Ramsey

Department of Chemistry,
University of North Carolina, USA
KN 02 - In-depth characterization of biopharmaceuticals using micropillar array columns combined with mass spectrometry
Koen Sandra

Research Institute for Chromatography,
Kortrijk, Belgium
11h45 Quantification of protein adsorption and optimization of separations in CE and CE-MS.
Hervé Cottet - Université de Montpellier, Institut des Biomolécules Max Mousseron, UMR CNRS 5247 - Montpellier, France
Charge variant analysis of monoclonal antibodies by CZE-MS under native conditions.
YS - Kendall Johnson - Barnett Institute of Chemical and Biological Analysis, Department of Chemistry and Chemical Biology, Northeastern University - Boston, USA
12h00 Evaluation of a nanoflow interface based on the triple-tube coaxial sheath-flow sprayer.
YS - Sabrina Ferré - Institute of Pharmaceutical Sciences of Western Switzerland, Group of Analytical Pharmaceutical Chemistry - Geneva, Switzerland
Online mass spectrometry of CE(SDS)-separated proteins by two-dimensional capillary electrophoresis.
YS - Jennifer Römer - Aalen University - Germany
12h15 Profiling nucleotides in low numbers of mammalian cells by sheathless CE-MS in positive ion mode: circumventing corona discharge.
Rawi Ramautar - Leiden University, Leiden Academic Center for Drug Research - Leiden, The Netherlands
The Detection of a reduced monoclonal antibody (mAb) at low ng/ml concentration in biological samples by CE-MS.
Karsten Hendriks - Sciex, Capillary Electrophoresis EMEAI
12h30 Characterization of post-transcriptional RNA modification by capillary electrophoresis - tandem mass spectrometry.
YS - Antony Lechner - CNRS – Unistra UMR 7140, Université de Strasbourg, Laboratoire de Spectrométrie de Masse des Interactions et des Systèmes - Strasbourg, France
Fab-specific peptide functionalized biomaterials for mAbs capture and analysis.
Zhengjin Jiang - Jinan University, institute of pharmaceutical analysis - Ganghzou, China
12h50 - 13h30  Workshop 
15h00 - 15h45   Seminar
15h50 Comprehensive omics
Chair: Alexander Ivanov
Northeastern University College of Science,
Boston, USA
Pharmaceuticals and drug development
Marianne Fillet
University of Liege, Liege, Belgium
15h55 KN 03 - Adventures in Multidimensional Fractionation for Quantitative Proteomics
Jarrod Marto

Dana-Farber Cancer Institute
and Harvard Medical School, Boston, USA
KN 04 - Quantitative microscale analytical systems to aid in drug development
Mike Roper

Department of Chemistry & Biochemistry,
The Florida State University, Florida,USA
16h20 Metabolic Trajectories Following Contrasting Diets from Food Provisions: Identifying Robust Biomarkers of Habitual Diet.
Philip Britz-Mc Kibbin - Mc Master University,Department of Chemistry and Chemical Biology - Hamilton, Canada
Direct analysis of glycosylation pattern of intact antibodies in cell supernatant with LC-MS or CE-MS.
Lukas Naumann - Faculty of Chemistry - Aalen University - Aalen, Germany
16h35 Genomics meets glycomics: a comprehensive omics approach for lung cancer biomarker discovery.
Andras Guttman - University of Pannonia - Hungary
The use of capillary electrophoresis in gene therapy product testing.
Stephen Lock - University of Pannonia / SCIEX
16h50 Native capillary electrophoresis top-down mass spectrometry for the characterization of proteoforms and their complexes.
YS - Kevin Jooss - Northwestern University, Departments of Chemistry and Molecular Biosciences - Evantson, USA
Characterization of antigen-adjuvant interactions in vaccines by Taylor dispersion analysis.
YS - Camille Malburet - IBMM, Institute of Biomolecules Max Mousseron - University of Montpellier, CNRS, ENSCM - Montpellier, France
17h05 Computer-assisted LC(CE)-HRMS analysis tools for untargeted analysis: sources of errors and strategies to overcome them.
Guillaume Erny - Faculdade de Engenharia da Universidade do Porto - Portugal
Fast and robust quality assessment of therapeutic monoclonal antibodies using size exclusion chromatography-mass spectrometry.
Raya A. Sadighi -Vrije University of Amsterdam, Division of Bio-Analytical Chemistry - Amsterdam, The Netherlands
WORKSHOP
17h30 - 17h50
Workshop: How to build an open-source capillary electrophoresis? Part 2
17h45 - 18h15 Poster session group 1
18h15 - 18h45 Poster session group 2
18h45 - 19h15 Poster session group 3
19h15 - 19h45 Poster session group 4
 
                    Tuesday 29th September 2020
9h00 Environmental analysis
Chair: Pham Hung Viet
Vietnam National University, Hanoi, Vietnam
Bioaffinity chromatography, monoliths and IMERs
Chair: Zhengjin Jiang
Jinan University, Ganghzou, China
9h05 KN 05 - HPLC coupled to high resolution mass spectrometry has boosted environmental research
Juliane Hollender

Department Environmental Chemistry, Federal Institute
of Aquatic Science and Technology (EAWAG),
Dübendorf, Switzerland
KN 06 - Chromatographic Imers as Prototypes for Flow-Chemistry Applications
Gabriella Massolini

Department of Pharmaceutical Sciences,
University of Pavia, Italy
9h30 Closing the Gap: Enrichment-free analysis of anionic persistent and mobile organic compounds in the sub-ppb range in drinking water by Capillary Electrophoresis-High Resolution Mass Spectrometry.
Christian Neusüss - Aalen University - Aalen, Germany
The potential of Porous Polymer Monoliths for sample preparation in capillary electrophoresis: From enrichment phases to microreactors.
Thuy Tran - Institut Galien Paris Sud, UMR8612, Protein and Nanotechnology in Analytical Science (PNAS), CNRS, Univ. Paris-Saclay - Châtenay-Malabry, France
9h45 Parallel coupling of nano-liquid chromatography with microarray bioassays and nanoelectrospray mass spectrometry for untargeted screening of toxic compounds.
Kristina Still - Vrije Universiteit, Division of Bioanalytical Chemistry - Amsterdam, The Netherlands
Ultra-miniaturized weak affinity chromatography for ligand identification of nanodiscs-solubilized G-protein coupled receptors: a new fragment screening approach in FBDD.
YS - Andrea Gottardini - Université de Lyon, Institut des Sciences Analytiques - Lyon, France
10h00 Development of a miniature and air-transportable liquid chromatograph with UV detector: Crude oil characterisation by GPC-UV.
Damien Bazin - Chromatotec, R&D service - Saint-Antoine, France
Affinity Sheathless CE-MS for the selective study of FcRn - Antibody interaction.
YS - Christopher Gstoettner - Leiden University Medical Center, Center for Proteomics and Metabolomics - Leiden - The Netherlands
10h20  Award Ceremony
PLENARY
LECTURE

10h25
Ion mobility and mass spectrometry detection for chip-based separation devices
Detlev Belder - Institut für Analytische Chemie, Fakultät für Chemie und Mineralogie,
Universität Leipzig, Germany
11h15 Food, beverages, nutrition and health
Chair: Ana M. García-Campaña
University of Granada, Granada, Spain
Biosensors, instrumentation and applications
Chair: Lorena Dieguez
International Iberian Nanotechnology Laboratory,
Braga, Portugal
11h20 KN 07 - Tailored micromotors for analyte (bio)sensing in health applications
Alberto Escarpa

Department of Analytical Chemistry and Chemical Engineering, University of Alcala de Henares, Spain
KN 08 - Current trends and applications in biosensors
Rita Asquini

Department of Information Engineering, Electronics and Telecommunications, Sapienza University, Rome, Italy
11h45 Analysis of nutritional and bioactive compounds in food supplements using purpose-made CE with contactless conductivity detection: a case study in Vietnam.
Pham Hung Viet- VNU University of Science, Vietnam National University,VNU Key Laboratory of Analytical Technology for Environmental Quality and Food Safety Control - Hanoi, Vitenam
Lab on a chip for the electrochemical quantitation and recycling of strategic material.
Anne Varenne - Institut of Chemistry for Life and Health Sciences, CNRS 2027, Chimie ParisTech PSL - Paris, France
12h00 Supercritical fluid chromatography tandem mass spectrometry combined with miniaturized extraction techniques as a promising tool for the analysis of vitamin D metabolites in biological samples.
YS - Bárbara Socas Rodríguez - Lund University, Green Technology Group - Lund, Sweden
Quantification of protein expression locally on tissue sections to evaluate tumor heterogeneity.
YS - Anna Fomitcheva Khartchenko - IBM Research, Precision Diagnostics - Zurich, Switzerland
12h15 Green micro-separation of phenolic acid and flavonoid using 3D printed lab on a chip device.
Haider Al Lawati  - Sultan Qaboos University, Chemistry - Oman
Pending
14h40 - 15h10 Poster session group 1
15h10 - 15h40 Poster session group 2
15h40 - 16h10 Poster session group 3
16h10 - 16h40 Poster session group 4
16h45 - 17h30  Seminar 
WORKSHOP
17h30 - 17h50
Workshop: How to build an open-source capillary electrophoresis? Part 3
18h00 Point-of-care devices, innovation in microfluidics,
precision medecine

Chair: Vince Remcho
Oregon State University, Corvallis, USA
Organ- and cell-on-chip
Chair: Stéphanie Descroix
Centre de recherche de l'Institut Curie, Paris, France
18h05 KN 09 - Advanced Tools in Precision Medicine: from 3D in vitro tissue models to point-of-care diagnostics
Frederic Zenhausern

University of Arizona, Phoenix, USA
KN 10 - Microscale biochemical assays for multiomic profiling of tumor sections
Govind Kaigala

IBM Research Laboratory, Zurich, Switzerland
18h30 Multiplexing Neurochemical Detection with Carbon Electrodes and Fast Scan Cyclic Voltammetry.
YS - Alexander Zestos - American University - Washington D.C., USA
Arrays of micro-magnets for negative selection of Circulating Tumor Cells in a microfluidic device.
YS - Lucie Descamps - Université Lyon 1,Institut des Nanotechnologies de Lyon - Lyon, France
18h45 Concentration and separation of DNA in complex biological fluids with µLAS technology.
Audrey Boutonnet-Rodat - ADELIS, R&D department - Labège, France
Extraction of NSAIDS and their metabolites from liver-on-chip samples by dispersive liquid-liquid microextraction based on the solidification of the floating organic drop.
YS - Maarten van der Horst - Hogeschool Leiden, LCAB - Leiden, The Netherlands
19h00 Capillary flow LC-MS usig micro pillar array columns: Combinig nano flowsensitivity with analytical flow robustness throughput.
Paul Jacobs  - PharmaFluidics, R&D - Ghent, Belgium
Fabrication of 2D monolayers and 3D spheroids of cells in acoustic levitation.
Nathan Jeger-Madiot - ESCPI / CNRS, PMMH - Paris, France
 
             Wednesday 30th September 2020
8h40 Electrodriven separations - AFSEP Session 1
Chair: Hervé Cottet
University of Montpellier, Montpellier, France
 
8h45 CE-ICP/MS and TDA/ICP-MS for the characterization of a therapeutic gadolinium-based nanoparticle.
YS - Lucie Labied - Institut des Sciences Analytiques, Techniques Séparatives - Lyon, France
9h00 Coupling on-chip HPLC and electrochromatography to ion mobility spectrometry.
YS - Nora Hartner - Leipzig University, Institute of Analytical Chemistry - Leipzig, Germany
9h15 ROMANCE strikes back: on the path to reliable CE-MS quantification.
Santiago Codesido Sanchez - Université de Genève, Analytical Sciences - Geneva, Switzerland
9h30 Analysis of lipid-conjugated oligonucleotides by cyclodextrin-modified capillary zone electrophoresis.
Fatima Barakat - Bordeaux University, ChemBioPharm team, ARNA INSERM U1212, CNRS 5320 - Bordeaux, France
9h45 Ultra-fast chiral separations of biomolecules by voltage-gradient gas-phase electrophoresis.
Govert W. Somsen - Division of Bioanalytical Chemistry, Amsterdam Institute for Molecules, Medicines and Systems - Amsterdam, The Netherlands
10h15 - 10h35  Seminar
10h40   Miniaturized sample preparation techniques
Chair: Hong Heng See
University of Technology Malaysia, Johor, Malaysia
10h45 Electrodriven separations - AFSEP Session 2
Chair: Yannis Francois
University of Strasbourg, Strasbourg, France
KN 11 - Liquid phase microextraction of biological samples – from principles to automation
Pavel Kuban

Institute of Analytical Chemistry of the Czech Academy
of Sciences, Brno, Czech Republic
10h55 Capillary electrophoresis tandem mass spectrometry for proteomics in the context of multiple myeloma: investigation of two hyphenating approaches.
YS - Marie-Jia Gou - University of Liege, Laboratory for The Analysis of Medicines - Liège, Belgium
11h10 Analysis and investigation of acid-base and electromigration properties of applied and potential peptide drugs by capillary electromigration methods.
Vaclav Kasicka - Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Electromigration methods - Prague, Czech Republic
On-chip sample preparation using a ChipFilter coupled to nanoLC-MS/MS for bottom-up proteomics.
Ndiaye Massamba Mbacké -  ESPCI Paris, Laboratoire de Spectrométrie de Masse Biologique et Protéomique SMBP - Paris, France
11h25 Physicochemical protein properties, quality and binding affinities.
Hermann Wätzig - Medicinal and Pharmaceutical Chemistry, Technical University - Braunschweig, Germany
Solid sampling probe based on a polymer inclusion membrane.
YS - Hui Yin Tey -University of Technology Malaysia, Centre for Sustainable and Nanomaterials - Johor, Malaysia
11h40 Metabo-ring study: a multi-center trial for the identification of metabolites in biological samples by CE-MS.
YS - Nicolas Drouin - Leiden University, Analytical Biosciences and Metabolomics - Leiden, The Netherlands
New approach for on-chip magnetic immuno-extraction of exosomes.
Monica Araya-Farias -Curie Institute, UMR 168 - Paris, France
11h55 Selection and application of markers for CE-DAD migration time correction of peptide maps used to assess enzyme activity.
Karen Waldron  - University of Montreal, Department of Chemistry - Montreal, Canada
Buffer exchange using bidirectional flow.
YS - Vesna Bacheva - IBM Research - Zurich, Suisse
Technion - Israel Institute of Technology, Science and Technology department - Haifa, Israël
12h15 - 13h00  Seminar
14h45 Portable and purpose-made devices
Chair: Peter Hauser
University of Basel, Basel, Switzerland
Biomarkers; clinical, diagnostic and forensic applications
Chairs: Frederic Robert - Sebia, Lisses, France
Philip Britz-McKibbin - McMaster University, Hamilton, Canada
14h50 KN 12 - A few contributions to the development of capillary electrophoresis systems
Claudimir Lucio do Lago

Institute of Chemistry, University of São Paulo,  Brasil
KN 13 - Capillary Electrophoresis application in Forensic Medicine and Science
Franco Tagliaro

Unit of Forensic Medicine, Department of Diagnostics
and Public Health, University of Verona, Verona, Italy
15h15 A portable CE-LIF prototype system of the Ocean Worlds Life Surveyor (OWLS) instrument suite for potential astrobiology spaceflight missions.
Florian Kehl - NASA Jet Propulsion Laboratory, California Institute of Technology Chemical Analysis and Life Detection - Pasadena, USA
In-depth characterization of glycated and carbamylated hemoglobin in clinical samples by top-down CE-MS/MS.
Alexander Stolz - Aalen University - Germany
15h30 A microfluidic HPLC-droplet-ESI-MS chip for the investigation of enzyme inhibitors.
YS - Andrea Peretzki -  Leipzig University, Institute of Analytical Chemistry - Leipzig, Germany
Capillary Isotachophoresis separation of exosomes.
Yuliya Shakalisava - Leiden University, Leiden Academic Center for Drug Research - Leiden, The Netherlands
15h45 Application of Microfluidic Glass-based Interfaces for 2D Electromigrative Separation Techniques.
YS - Hannes Graf  - Eberhard Karls Universität Tübingen, Institute of Physical and Theoretical Chemistry - Tübingen, Germany
Deep and highly sensitive CZE-MS-based glycan profiling of human plasma and blood-derived immunoglobulin G and extracellular vesicle isolates.
Alexander Ivanov - Northeastern University College of Science, Department of Chemistry and Chemical Biology - Boston, USA
16h00 A new concept for modular CE with LiF detection: a highlight with O-glycans analysis.
YS - Théo Liénard--Mayor - Institut Galien Paris-Sud, PNAS - Chatenay-Malabry, France
Steroid profile in human seminal fluid: is it linked to sperm quality?
YS - Eulalia Olesti - Biomedical and metabolomics analysis, Analytical Sciences, University of Geneva - Geneva, Switzerland
PLENARY
LECTURE

16h35 - 17h15
New developments in metabolomics with CE-MS
Coral Barbas - Center for Metabolomics and Bioanalysis (CEMBIO) - Universidad San Pablo CEU - Madrid, Spain
17h15 - 17h30 Awards/Prizes ceremony
WORKSHOP
17h30 - 17h50
Workshop: How to build an open-source capillary electrophoresis? Part 4
17h50 - 18h00 MSB 2021
18h00 - 18h15 Closing ceremony