The COVID-19 outbreak brings an increasing number of concerns.
The organizing committee has decided to postpone MSB to ensure the safety of our delegates.

New dates : 27-30th September, 2020.

 

Detailed scientific program
YS : Young Scientist                                                                                           Subject to change and availability of speakers

 

Sunday 27th September, 2020
From 12h00 Registration
13h30 - 16h30
  • Short course 1: Facing the complexity of biopharmaceuticals characterisation - by Davy Guillarme and Yannis François
  • Short course 2: Introduction to metabolomics workflow - by Coral Barbas and Serge Rudaz
  • Short course 3: From Validation to Uncertainty: Taking the Best from Regulations in Bioanalysis - by Jean-Marc Roussel
  • Workshop: How to build an open-source capillary electrophoresis? - by Olivier Vorlet and Samuel Roth
17h15 Opening ceremony
Chairs: Pr Myrian Taverna - University Paris-Saclay - Chatenay-Malabry, France
& Pr Serge Rudaz - University of Geneva - Switzerland
17h40 - 18h30

PLENARY
LECTURE
The modular proteome and its biological significance
Ruedi Aebersold - Department of Biology, Institute of Molecular Systems Biology, ETH  Zurich and Faculty of Science,
 University of Zurich - Zurich, Switzerland
18h30 - 18h50 Start-up session           

19h00 - 23h00
 
Welcome reception


 

 

Monday 28th September, 2020
From 12h00 Registration

 

Auditorium - Level 2 Sea view room - Level 3
8h20 - 9h10

PLENARY
LECTURE
                                  Designing materials for ultrasensitive biosensing             
Molly M. Stevens
Department of Materials, Department of Bioengineering and Institute of Biomedical Engineering,
Imperial College - London, United Kingdom
9h15 CE-MS and advances in instrumentation
Chair: Christian Neusüß
Aalen University, Aalen, Germany
Biomarkers; clinical, diagnostic and forensic applications
Chairs: Frederic Robert - Sebia, Lisses, France
Philip Britz-McKibbin - McMaster University, Hamilton, Canada
9h20 KN 01 - Microchip CE: Characterizing Molecules Large-to-Small using Mass Spectrometers Large-to-Small
Michael Ramsey
Department of Chemistry, University of North Carolina, USA
KN 02 - Capillary Electrophoresis application in Forensic Medicine and Science
Franco Tagliaro
Unit of Forensic Medicine, Department of Diagnostics
and Public Health, University of Verona, Verona, Italy
9h50 Quantification of protein adsorption and optimization of separations
in CE and CE-MS.

Hervé Cottet - Université de Montpellier, Institut des Biomolécules Max Mousseron,
UMR CNRS 5247 - Montpellier, France
 In-depth characterization of glycated and carbamylated hemoglobin in clinical samples by top-down CE-MS/MS.
Alexander Stolz - Aalen University - Germany
10h10 Evaluation of a nanoflow interface based on the triple-tube coaxial sheath-flow sprayer.
YS - Sabrina Ferré - Institute of Pharmaceutical Sciences of Western Switzerland,
Group of Analytical Pharmaceutical Chemistry - Geneva, Switzerland
Capillary Isotachophoresis separation of exosomes.
Yuliya Shakalisava - Leiden University, Leiden Academic Center for Drug Research - Leiden, The Netherlands

10h30 - 11h00
 
Coffee break
11h00 Profiling nucleotides in low numbers of mammalian cells by sheathless CE-MS
in positive ion mode: circumventing corona discharge.

Rawi Ramautar - Leiden University, Leiden Academic Center for Drug Research -
Leiden, The Netherlands
Deep and highly sensitive CZE-MS-based glycan profiling of human plasma and blood-derived immunoglobulin G and extracellular vesicle isolates.
Alexander Ivanov - Northeastern University College of Science, Department of Chemistry and Chemical Biology - Boston, USA
11h20 Characterization of post-transcriptional RNA modification by capillary electrophoresis - tandem mass spectrometry.
YS - Antony Lechner - CNRS – Unistra UMR 7140, Université de Strasbourg, Laboratoire de Spectrométrie de Masse des Interactions et des Systèmes - Strasbourg, France
Steroid profile in human seminal fluid: is it linked to sperm quality?
YS - Eulalia Olesti - Biomedical and metabolomics analysis, Analytical Sciences,
University of Geneva - Geneva, Switzerland
11h50 - 12h40 RSC (Royal Society of Chemistry) Workshop
12h45 - 13h30 Lunch seminar AGILENT TECHNOLOGIES
13h30 - 14h30 Poster session 1   
14h30 Environmental analysis
Chair: Pham Hung Viet
Vietnam National University, Hanoi, Vietnam
Bioaffinity chromatography, monoliths and IMERs
Chair: Zhengjin Jiang
Jinan University, Guangzhou, China
14h35 KN 03 - HPLC coupled to high resolution mass spectrometry has boosted environmental research
Juliane Hollender
Department Environmental Chemistry, Federal Institute of Aquatic Science and Technology (EAWAG), Dübendorf, Switzerland
KN 04 - Chromatographic Imers as Prototypes for Flow-Chemistry Applications
Gabriella Massolini
Department of Pharmaceutical Sciences, University of Pavia, Italy
15h05 Closing the Gap: Enrichment-free analysis of anionic persistent and mobile organic compounds in the sub-ppb range in drinking water by Capillary Electrophoresis-High Resolution Mass Spectrometry.
Christian Neusüß - Aalen University - Aalen, Germany
The potential of porous polymer monoliths for sample preparation in capillary electrophoresis: From enrichment phases to microreactors.
Thuy Tran - Institut Galien Paris Sud, UMR8612, Protein and Nanotechnology in Analytical Science (PNAS), CNRS, Univ. Paris-Saclay - Châtenay-Malabry, France
15h25 Parallel coupling of nano-liquid chromatography with microarray bioassays and nanoelectrospray mass spectrometry for untargeted screening of toxic compounds.
Kristina Still - Vrije Universiteit, Division of Bioanalytical Chemistry -
Amsterdam, The Netherlands
Ultra-miniaturized weak affinity chromatography for ligand identification of nanodiscs-solubilized G-protein coupled receptors: a new fragment screening approach in FBDD.
YS - Andrea Gottardini - Université de Lyon, Institut des Sciences Analytiques
Lyon, France
15h45 Development of a miniature and air-transportable liquid chromatograph with UV detector: Crude oil characterisation by GPC-UV.
Damien Bazin - Chromatotec, R&D service - Saint-Antoine, France
Affinity Sheathless CE-MS for the selective study of FcRn - Antibody interaction.
YS - Christopher Gstöttner - Leiden University Medical Center, Center for Proteomics and Metabolomics - Leiden - The Netherlands

16h05 - 16h45
 
Coffee break
16h45 Food, beverages, nutrition and health
Chair: Ana M. García-Campaña
University of Granada, Granada, Spain
Biosensors, instrumentation and applications
Chair: Lorena Dieguez
International Iberian Nanotechnology Laboratory, Braga, Portugal
16h50 KN 05 - Tailored micromotors for analyte (bio)sensing in health applications
Alberto Escarpa
Department of Analytical Chemistry and Chemical Engineering,
University of Alcala de Henares, Spain
KN 06 - Current trends and applications in biosensors
Rita Asquini
Department of Information Engineering, Electronics and Telecommunications, Sapienza University, Rome, Italy
17h20 Analysis of nutritional and bioactive compounds in food supplements using purpose-made CE with contactless conductivity detection: a case study in Vietnam.
Hung Viet Pham - VNU University of Science, Vietnam National University,
VNU Key Laboratory of Analytical Technology for Environmental Quality
and Food Safety Control - Hanoi, Vietnam
Lab on a chip for the electrochemical quantitation and recycling of strategic material.
Anne Varenne - Institute of Chemistry for Life and Health Sciences, CNRS 2027,
Chimie ParisTech PSL - Paris, France
17h40 Supercritical fluid chromatography tandem mass spectrometry combined with miniaturized extraction techniques as a promising tool for the analysis of vitamin D metabolites in biological samples.
YS - Bárbara Socas Rodríguez - Lund University, Green Technology Group - Lund, Sweden
Development of Automated Microchip Electrophoresis Hardware for Life Detection.
Maria Fernanda Mora - Jet Propulsion Laboratory, California Institute of Technology, Chemical Analysis and Life Detection Group - Pasadena, USA
18h00 Green micro-separation of phenolic acid and flavonoid
using 3D printed lab on a chip device.

Haider Al Lawati  - Sultan Qaboos University, Chemistry - Oman
Quantification of protein expression locally on tissue sections
to evaluate tumor heterogeneity.

YS - Anna Fomitcheva Khartchenko - IBM Research, Precision Diagnostics -
Zurich, Switzerland

19h30 - 22h30
 
Gala dinner


 

 

Tuesday 29th September, 2020

 

Auditorium - Level 2 Sea view room - Level 3
8h20  SCIEX Award Ceremony
8h30 - 9h20

SCIEX AWARD
Ion mobility and mass spectrometry detection for chip-based separation devices
Detlev Belder
Institut für Analytische Chemie, Fakultät für Chemie und Mineralogie, 
Universität Leipzig, Germany
9h30 Portable and purpose-made devices
Chair: Peter Hauser
University of Basel, Basel, Switzerland
Comprehensive omics
Chair: Alexander Ivanov
Northeastern University College of Science, Boston, USA
9h35 KN 07 - A few contributions to the development of capillary
electrophoresis systems

Claudimir Lucio do Lago

Institute of Chemistry, University of São Paulo,  Brasil
KN 08 - Adventures in Multidimensional Fractionation
or Quantitative Proteomics

Jarrod Marto

Dana-Farber Cancer Institute and Harvard Medical School, Boston, USA
10h05 Portable and modular capillary HPLC solutions for the pharmaceutical industry.
Brett Paull - University of Tasmania, Australian Centre
for Research in Separation Science - Australia
Metabolic Trajectories Following Contrasting Diets from Food Provisions: Identifying Robust Biomarkers of Habitual Diet.
Philip Britz-Mc Kibbin - Mc Master University,
Department of Chemistry and Chemical Biology - Hamilton, Canada
10h25 A portable CE-LIF prototype system of the Ocean Worlds Life Surveyor (OWLS) instrument suite for potential astrobiology spaceflight missions.
Florian Kehl - NASA Jet Propulsion Laboratory, California Institute of Technology Chemical Analysis and Life Detection - Pasadena, USA
Genomics meets glycomics: a comprehensive omics approach for lung cancer biomarker discovery.
Andras Guttman - University of Pannonia - Hungary

10h45 - 11h15
 
Coffee break
11h15 A microfluidic HPLC-droplet-ESI-MS chip for the investigation of enzyme inhibitors.
YS - Andrea Peretzki -  Leipzig University, Institute of Analytical Chemistry -
Leipzig, Germany
Native capillary electrophoresis top-down mass spectrometry for the characterization of proteoforms and their complexes.
YS - Kevin Jooss - Northwestern University, Departments of Chemistry and Molecular Biosciences - Evantson, USA
11h35 Application of Microfluidic Glass-based Interfaces for 2D Electromigrative Separation Techniques.
YS - Benjamin Rudisch - Eberhard Karls Universität Tübingen, Institute of Physical
and Theoretical Chemistry - Tübingen, Germany
Metabo-ring study: a multi-center trial for the identification of metabolites in biological samples by CE-MS.
YS - Nicolas Drouin - Leiden University, Analytical Biosciences and Metabolomics -
Leiden, The Netherlands
11h55 A new concept for modular CE with LIF detection: a highlight with N-glycans analysis. 
YS - Théo Liénard-Mayor - Institut Galien Paris-Sud, PNAS - Chatenay-Malabry, France
Computer-assisted LC(CE)-HRMS analysis tools for untargeted analysis: sources of errors and strategies to overcome them.
Guillaume Erny - Faculdade de Engenharia da Universidade do Porto - Portuga
l
12h15 - 13h00 Lunch seminar VICI
13h00 - 14h00 Poster session 2
14h00 Point-of-care devices, innovation in microfluidics, precision medicine
Chair: Vince Remcho
Oregon State University, Corvallis, USA
Organ- and cell-on-chip
Chair: Stéphanie Descroix
Centre de recherche de l'Institut Curie, Paris, France
14h05 KN 09 - Advanced Tools in Precision Medicine: from 3D in vitro tissue models to point-of-care diagnostics
Frederic Zenhausern
University of Arizona, Phoenix, USA
KN 10 - Microscale biochemical assays for multiomic profiling of tumor sections
Govind Kaigala

IBM Research Laboratory, Zurich, Switzerland
14h35 Multiplexing Neurochemical Detection with Carbon Electrodes and Fast Scan Cyclic Voltammetry.
YS - Alexander Zestos - American University - Washington D.C., USA
Arrays of micro-magnets for negative selection of Circulating Tumor Cells in a microfluidic device.
YS - Lucie Descamps - Université Lyon 1, Institut des Nanotechnologies de Lyon -
Lyon, France
14h55 Concentration and separation of DNA in complex biological fluids
with µLAS technology.

Audrey Boutonnet-Rodat - ADELIS, R&D department - Labège, France
Extraction of NSAIDS and their metabolites from liver-on-chip samples
by dispersive liquid-liquid microextraction based on the solidification
of the floating organic drop.

YS - Maarten van der Horst - Hogeschool Leiden, LCAB - Leiden, The Netherlands
15h15 Capillary flow LC-MS using micro pillar array columns: Combining nano flow sensitivity with analytical flow robustness throughput.
Paul Jacobs - PharmaFluidics, R&D - Ghent, Belgium
Fabrication of 2D monolayers and 3D spheroids of cells in acoustic levitation.
Nathan Jeger-Madiot - ESPCI / CNRS, PMMH - Paris, France

15h40-22h00
 
          Social event: Mont Saint-Michel          
Return to Saint-Malo before 22h30, dinner on your own.


 

 

Wednesday 30th September, 2020

 

Auditorium - Level 2 Sea view room - Level 3
8h05 Electrodriven separations - AFSEP Session    
Chairs: Hervé Cottet - University of Montpellier, Montpellier, France
Yannis Francois - University of Strasbourg, Strasbourg, France
Biopharmaceuticals
Chair: Davy Guillarme
University of Geneva, Geneva, Switzerland
Session begins at 8:15
8h10 CE-ICP/MS and TDA/ICP-MS for the characterization of a therapeutic gadolinium-based nanoparticle.
YS - Lucie Labied - Institut des Sciences Analytiques, Techniques Séparatives
Lyon, France
KN 11 - In-depth characterization of biopharmaceuticals using micropillar array columns combined with mass spectrometry
Koen Sandra

Research Institute for Chromatography, Kortrijk, Belgium
Keynote lecture begins at 8:20
8h30 Coupling on-chip HPLC and electrochromatography to ion mobility spectrometry.
YS - Nora Hartner - Leipzig University, Institute of Analytical Chemistry
Leipzig, Germany
8h50 ROMANCE strikes back: on the path to reliable CE-MS quantification.
Santiago Codesido Sanchez - Université de Genève, Analytical Sciences -
Geneva, Switzerland
Physicochemical protein properties, quality and binding affinities.
Hermann Wätzig - Medicinal and Pharmaceutical Chemistry, Technical University - Braunschweig, Germany
9h10 Analysis of lipid-conjugated oligonucleotides by cyclodextrin-modified capillary zone electrophoresis.
Fatima Barakat - Bordeaux University, ChemBioPharm team, ARNA INSERM U1212,
CNRS 5320 - Bordeaux, France
Charge variant analysis of monoclonal antibodies by CZE-MS under native conditions.
YS - Kendall Johnson - Barnett Institute of Chemical and Biological Analysis,
Department of Chemistry and Chemical Biology, Northeastern University - Boston, USA
9h30 Ultra-fast chiral separations of biomolecules by voltage-gradient gas-phase electrophoresis.
Govert W. Somsen - Division of Bioanalytical Chemistry, Amsterdam Institute for Molecules, Medicines and Systems - Amsterdam, The Netherlands
Online mass spectrometry of CE(SDS)-separated proteins by two-dimensional capillary electrophoresis.
YS - Jennifer Römer - Aalen University - Aelen, Germany
9h50 Capillary electrophoresis tandem mass spectrometry for proteomics in the context of multiple myeloma: investigation of two hyphenating approaches.
YS - Marie-Jia Gou - University of Liege, Laboratory for The Analysis of Medicines -
Liège, Belgium
The Detection of a reduced monoclonal antibody (mAb) at low ng/ml concentration in biological samples by CE-MS.
Karsten Hendriks - Sciex, Capillary Electrophoresis EMEAI
10h10 Analysis and investigation of acid-base and electromigration properties of applied and potential peptide drugs by capillary electromigration methods.
Vaclav Kasicka - Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Electromigration methods - Prague, Czech Republic
Fab-specific peptide functionalized biomaterials for mAbs capture and analysis.
Zhengjin Jiang - Jinan University, institute of pharmaceutical analysis -
Guangzhou, China

10h30 - 11h00
 
Coffee break
11h00 Miniaturized sample preparation techniques
Chair: Hong Heng See
University of Technology Malaysia, Johor, Malaysia
Pharmaceuticals and drug development
Chair: Marianne Fillet
University of Liege, Belgium
11h05 KN 12 - Liquid phase microextraction of biological samples – from principles to automation
Pavel Kuban

Institute of Analytical Chemistry of the Czech Academy
of Sciences, Brno, Czech Republic
KN 13 - Quantitative microscale analytical systems to aid in drug development
Mike Roper

Department of Chemistry & Biochemistry, 
The Florida State University, Florida,USA
11h35 On-chip sample preparation using a ChipFilter coupled to nanoLC-MS/MS
for bottom-up proteomics.

Ndiaye Massamba Mbacké -  ESPCI Paris, Laboratoire de Spectrométrie de Masse Biologique et Protéomique SMBP - Paris, France
Direct analysis of glycosylation pattern of intact antibodies in cell supernatant
with LC-MS or CE-MS.

Lukas Naumann - Faculty of Chemistry - Aalen University - Aalen, Germany
11h55 Solid sampling probe based on a polymer inclusion membrane.
YS - Hui Yin Tey -University of Technology Malaysia, Centre for Sustainable
and Nanomaterials - Johor, Malaysia
The use of capillary electrophoresis in gene therapy product testing.
Stephen Lock - University of Pannonia - Hungary
SCIEX -United Kingdom
12h15 - 12h30 Lunch
12h30 - 12h40 Participant special award
12h40 - 13h25 Poster pitches session
13h30 New approach for on-chip magnetic immuno-extraction of exosomes.
Monica Araya-Farias -Curie Institute, UMR 168 - Paris, France
Characterization of antigen-adjuvant interactions in vaccines
by Taylor dispersion analysis

YS - Camille Maburet - IBMM, Institute of Biomolecules Max Mousseron - University of Montpellier, CNRS, ENSCM - Montpellier, France
13h50 Buffer exchange using bidirectional flow.
YS - Vesna Bacheva - IBM Research - Zurich, Switzerland
Technion - Israel Institute of Technology, Science and Technology department -
Haifa, Israël
Fast and robust quality assessment of therapeutic monoclonal antibodies using size exclusion chromatography-mass spectrometry.
Raya A. Sadighi -Vrije University of Amsterdam, Division of Bio-Analytical Chemistry - Amsterdam, The Netherlands
14h10 Selection and application of markers for CE-DAD migration time correction of peptide maps used to assess enzyme activity.
Karen Waldron  - University of Montreal, Department of Chemistry - Montreal, Canada
Ideal-Filter Capillary Electrophoresis: a Disruptive Technology for Drug Development from DNA-Encoded Libraries (DELs).
Sergey Krylov -York University, Department of Chemistry - York, Canada
14h35 - 15h25

PLENARY
LECTURE
New developments in metabolomics with CE-MS
Coral Barbas
Center for Metabolomics and Bioanalysis (CEMBIO), Universidad San Pablo CEU - Madrid, Spain
15h25 - 15h45 Award/Prize ceremony
15h45 - 15h55 MSB 2021
15h55 - 16h15 Closing ceremony
Chairs: Pr Myriam Taverna - University Paris-Saclay - Chatenay-Malabry, France
Pr Serge Rudaz - University of Geneva - Switzerland
16h15 - 17h00 Farewell drink


Program subject to change in accordance with the availability of some speakers.