To safeguard the health of all participants, and in agreement with the SMSB Board, we have decided to translate the original MSB 2020 program to a 100% virtual format, with the support of Imavox, a world leader in the field of virtual events with over 20 years of experience.
New dates : 27-30th September, 2020.
Detailed scientific program
YS : Young Scientist Program subject to change in accordance with the availability of some speakers.
|Sunday 27th September 2020|
10h00 - 12h30
|Introduction to metabolomics workflow
by Coral Barbas and Serge Rudaz
|Facing the complexity of biopharmaceuticals characterisation
Davy Guillarme and Yannis François
13h00 - 15h30
|From Validation to Uncertainty: Taking the Best from Regulations in Bioanalysis
Chairs: Pr Myriam Taverna - University Paris Saclay - Chatenay-Malabry, France
& Pr Serge Rudaz - University of Geneva - Switzerland
16h00 - 16h40
|The modular proteome and its biological significance
Ruedi Aebersold - Department of Biology, Institute of Molecular Systems Biology,
ETH Zurich and Faculty of Science, University of Zurich - Zurich, Switzerland
|16h45 - 17h30||Start-up session|
WORKSHOP17h30 - 17h50
|Workshop: How to build an open-source capillary electrophoresis? Part 1|
|Monday 28th September 2020|
10h30 - 11h10
| Designing materials for ultrasensitive biosensing
Molly M. Stevens - Department of Materials, Department of Bioengineering
and Institute of Biomedical Engineering, Imperial College - London, United Kingdom
|11h15||CE-MS and advances in instrumentation
Chair: Christian Neusüss
Aalen University, Aalen, Germany
Chair: Davy Guillarme
University of Geneva, Geneva, Switzerland
|11h20||KN 01 - Microchip CE: Characterizing Molecules Large-to-Small using Mass Spectrometers Large-to-Small
Department of Chemistry,
University of North Carolina, USA
|KN 02 - In-depth characterization of biopharmaceuticals using micropillar array columns combined with mass spectrometry
Research Institute for Chromatography,
|11h45||Quantification of protein adsorption and optimization of separations in CE and CE-MS.
Hervé Cottet - Université de Montpellier, Institut des Biomolécules Max Mousseron, UMR CNRS 5247 - Montpellier, France
|Charge variant analysis of monoclonal antibodies by CZE-MS under native conditions.
YS - Kendall Johnson - Barnett Institute of Chemical and Biological Analysis, Department of Chemistry and Chemical Biology, Northeastern University - Boston, USA
|12h00||Evaluation of a nanoflow interface based on the triple-tube coaxial sheath-flow sprayer.
YS - Sabrina Ferré - Institute of Pharmaceutical Sciences of Western Switzerland, Group of Analytical Pharmaceutical Chemistry - Geneva, Switzerland
|Online mass spectrometry of CE(SDS)-separated proteins by two-dimensional capillary electrophoresis.
YS - Jennifer Römer - Aalen University - Germany
|12h15||Profiling nucleotides in low numbers of mammalian cells by sheathless CE-MS in positive ion mode: circumventing corona discharge.
Rawi Ramautar - Leiden University, Leiden Academic Center for Drug Research - Leiden, The Netherlands
|The Detection of a reduced monoclonal antibody (mAb) at low ng/ml concentration in biological samples by CE-MS.
Karsten Hendriks - Sciex, Capillary Electrophoresis EMEAI
|12h30||Characterization of post-transcriptional RNA modification by capillary electrophoresis - tandem mass spectrometry.
YS - Antony Lechner - CNRS – Unistra UMR 7140, Université de Strasbourg, Laboratoire de Spectrométrie de Masse des Interactions et des Systèmes - Strasbourg, France
|Fab-specific peptide functionalized biomaterials for mAbs capture and analysis.
Zhengjin Jiang - Jinan University, institute of pharmaceutical analysis - Ganghzou, China
|12h50 - 13h30||Workshop|
|15h00 - 15h45||Seminar|
Chair: Alexander Ivanov
Northeastern University College of Science,
|Pharmaceuticals and drug development
University of Liege, Liege, Belgium
|15h55||KN 03 - Adventures in Multidimensional Fractionation for Quantitative Proteomics
Dana-Farber Cancer Institute
and Harvard Medical School, Boston, USA
|KN 04 - Quantitative microscale analytical systems to aid in drug development
Department of Chemistry & Biochemistry,
The Florida State University, Florida,USA
|16h20||Metabolic Trajectories Following Contrasting Diets from Food Provisions: Identifying Robust Biomarkers of Habitual Diet.
Philip Britz-Mc Kibbin - Mc Master University,Department of Chemistry and Chemical Biology - Hamilton, Canada
|Direct analysis of glycosylation pattern of intact antibodies in cell supernatant with LC-MS or CE-MS.
Lukas Naumann - Faculty of Chemistry - Aalen University - Aalen, Germany
|16h35||Genomics meets glycomics: a comprehensive omics approach for lung cancer biomarker discovery.
Andras Guttman - University of Pannonia - Hungary
|The use of capillary electrophoresis in gene therapy product testing.
Stephen Lock - University of Pannonia / SCIEX
|16h50||Native capillary electrophoresis top-down mass spectrometry for the characterization of proteoforms and their complexes.
YS - Kevin Jooss - Northwestern University, Departments of Chemistry and Molecular Biosciences - Evantson, USA
|Characterization of antigen-adjuvant interactions in vaccines by Taylor dispersion analysis.
YS - Camille Malburet - IBMM, Institute of Biomolecules Max Mousseron - University of Montpellier, CNRS, ENSCM - Montpellier, France
|17h05||Computer-assisted LC(CE)-HRMS analysis tools for untargeted analysis: sources of errors and strategies to overcome them.
Guillaume Erny - Faculdade de Engenharia da Universidade do Porto - Portugal
|Fast and robust quality assessment of therapeutic monoclonal antibodies using size exclusion chromatography-mass spectrometry.
Raya A. Sadighi -Vrije University of Amsterdam, Division of Bio-Analytical Chemistry - Amsterdam, The Netherlands
17h30 - 17h50
|Workshop: How to build an open-source capillary electrophoresis? Part 2|
|17h45 - 18h15||Poster session group 1|
|18h15 - 18h45||Poster session group 2|
|18h45 - 19h15||Poster session group 3|
|19h15 - 19h45||Poster session group 4|
|Tuesday 29th September 2020|
Chair: Pham Hung Viet
Vietnam National University, Hanoi, Vietnam
|Bioaffinity chromatography, monoliths and IMERs
Chair: Zhengjin Jiang
Jinan University, Ganghzou, China
|9h05||KN 05 - HPLC coupled to high resolution mass spectrometry has boosted environmental research
Department Environmental Chemistry, Federal Institute
of Aquatic Science and Technology (EAWAG),
|KN 06 - Chromatographic Imers as Prototypes for Flow-Chemistry Applications
Department of Pharmaceutical Sciences,
University of Pavia, Italy
|9h30||Closing the Gap: Enrichment-free analysis of anionic persistent and mobile organic compounds in the sub-ppb range in drinking water by Capillary Electrophoresis-High Resolution Mass Spectrometry.
Christian Neusüss - Aalen University - Aalen, Germany
|The potential of Porous Polymer Monoliths for sample preparation in capillary electrophoresis: From enrichment phases to microreactors.
Thuy Tran - Institut Galien Paris Sud, UMR8612, Protein and Nanotechnology in Analytical Science (PNAS), CNRS, Univ. Paris-Saclay - Châtenay-Malabry, France
|9h45||Parallel coupling of nano-liquid chromatography with microarray bioassays and nanoelectrospray mass spectrometry for untargeted screening of toxic compounds.
Kristina Still - Vrije Universiteit, Division of Bioanalytical Chemistry - Amsterdam, The Netherlands
|Ultra-miniaturized weak affinity chromatography for ligand identification of nanodiscs-solubilized G-protein coupled receptors: a new fragment screening approach in FBDD.
YS - Andrea Gottardini - Université de Lyon, Institut des Sciences Analytiques - Lyon, France
|10h00||Development of a miniature and air-transportable liquid chromatograph with UV detector: Crude oil characterisation by GPC-UV.
Damien Bazin - Chromatotec, R&D service - Saint-Antoine, France
|Affinity Sheathless CE-MS for the selective study of FcRn - Antibody interaction.
YS - Christopher Gstoettner - Leiden University Medical Center, Center for Proteomics and Metabolomics - Leiden - The Netherlands
|Ion mobility and mass spectrometry detection for chip-based separation devices
Detlev Belder - Institut für Analytische Chemie, Fakultät für Chemie und Mineralogie,
Universität Leipzig, Germany
|11h15||Food, beverages, nutrition and health
Chair: Ana M. García-Campaña
University of Granada, Granada, Spain
|Biosensors, instrumentation and applications
Chair: Lorena Dieguez
International Iberian Nanotechnology Laboratory,
|11h20||KN 07 - Tailored micromotors for analyte (bio)sensing in health applications
Department of Analytical Chemistry and Chemical Engineering, University of Alcala de Henares, Spain
|KN 08 - Current trends and applications in biosensors
Department of Information Engineering, Electronics and Telecommunications, Sapienza University, Rome, Italy
|11h45||Analysis of nutritional and bioactive compounds in food supplements using purpose-made CE with contactless conductivity detection: a case study in Vietnam.
Pham Hung Viet- VNU University of Science, Vietnam National University,VNU Key Laboratory of Analytical Technology for Environmental Quality and Food Safety Control - Hanoi, Vitenam
|Lab on a chip for the electrochemical quantitation and recycling of strategic material.
Anne Varenne - Institut of Chemistry for Life and Health Sciences, CNRS 2027, Chimie ParisTech PSL - Paris, France
|12h00||Supercritical fluid chromatography tandem mass spectrometry combined with miniaturized extraction techniques as a promising tool for the analysis of vitamin D metabolites in biological samples.
YS - Bárbara Socas Rodríguez - Lund University, Green Technology Group - Lund, Sweden
|Quantification of protein expression locally on tissue sections to evaluate tumor heterogeneity.
YS - Anna Fomitcheva Khartchenko - IBM Research, Precision Diagnostics - Zurich, Switzerland
|12h15||Green micro-separation of phenolic acid and flavonoid using 3D printed lab on a chip device.
Haider Al Lawati - Sultan Qaboos University, Chemistry - Oman
|14h40 - 15h10||Poster session group 1|
|15h10 - 15h40||Poster session group 2|
|15h40 - 16h10||Poster session group 3|
|16h10 - 16h40||Poster session group 4|
|16h45 - 17h30||Seminar|
17h30 - 17h50
|Workshop: How to build an open-source capillary electrophoresis? Part 3|
|18h00||Point-of-care devices, innovation in microfluidics,
Chair: Vince Remcho
Oregon State University, Corvallis, USA
|Organ- and cell-on-chip
Chair: Stéphanie Descroix
Centre de recherche de l'Institut Curie, Paris, France
|18h05||KN 09 - Advanced Tools in Precision Medicine: from 3D in vitro tissue models to point-of-care diagnostics
University of Arizona, Phoenix, USA
|KN 10 - Microscale biochemical assays for multiomic profiling of tumor sections
IBM Research Laboratory, Zurich, Switzerland
|18h30||Multiplexing Neurochemical Detection with Carbon Electrodes and Fast Scan Cyclic Voltammetry.
YS - Alexander Zestos - American University - Washington D.C., USA
|Arrays of micro-magnets for negative selection of Circulating Tumor Cells in a microfluidic device.
YS - Lucie Descamps - Université Lyon 1,Institut des Nanotechnologies de Lyon - Lyon, France
|18h45||Concentration and separation of DNA in complex biological fluids with µLAS technology.
Audrey Boutonnet-Rodat - ADELIS, R&D department - Labège, France
|Extraction of NSAIDS and their metabolites from liver-on-chip samples by dispersive liquid-liquid microextraction based on the solidification of the floating organic drop.
YS - Maarten van der Horst - Hogeschool Leiden, LCAB - Leiden, The Netherlands
|19h00||Capillary flow LC-MS usig micro pillar array columns: Combinig nano flowsensitivity with analytical flow robustness throughput.
Paul Jacobs - PharmaFluidics, R&D - Ghent, Belgium
|Fabrication of 2D monolayers and 3D spheroids of cells in acoustic levitation.
Nathan Jeger-Madiot - ESCPI / CNRS, PMMH - Paris, France
|Wednesday 30th September 2020|
|8h40||Electrodriven separations - AFSEP Session 1
Chair: Hervé Cottet
University of Montpellier, Montpellier, France
|8h45||CE-ICP/MS and TDA/ICP-MS for the characterization of a therapeutic gadolinium-based nanoparticle.
YS - Lucie Labied - Institut des Sciences Analytiques, Techniques Séparatives - Lyon, France
|9h00||Coupling on-chip HPLC and electrochromatography to ion mobility spectrometry.
YS - Nora Hartner - Leipzig University, Institute of Analytical Chemistry - Leipzig, Germany
|9h15||ROMANCE strikes back: on the path to reliable CE-MS quantification.
Santiago Codesido Sanchez - Université de Genève, Analytical Sciences - Geneva, Switzerland
|9h30||Analysis of lipid-conjugated oligonucleotides by cyclodextrin-modified capillary zone electrophoresis.
Fatima Barakat - Bordeaux University, ChemBioPharm team, ARNA INSERM U1212, CNRS 5320 - Bordeaux, France
|9h45||Ultra-fast chiral separations of biomolecules by voltage-gradient gas-phase electrophoresis.
Govert W. Somsen - Division of Bioanalytical Chemistry, Amsterdam Institute for Molecules, Medicines and Systems - Amsterdam, The Netherlands
|10h15 - 10h35||Seminar|
|10h40||Miniaturized sample preparation techniques
Chair: Hong Heng See
University of Technology Malaysia, Johor, Malaysia
|10h45||Electrodriven separations - AFSEP Session 2
Chair: Yannis Francois
University of Strasbourg, Strasbourg, France
|KN 11 - Liquid phase microextraction of biological samples – from principles to automation
Institute of Analytical Chemistry of the Czech Academy
of Sciences, Brno, Czech Republic
|10h55||Capillary electrophoresis tandem mass spectrometry for proteomics in the context of multiple myeloma: investigation of two hyphenating approaches.
YS - Marie-Jia Gou - University of Liege, Laboratory for The Analysis of Medicines - Liège, Belgium
|11h10||Analysis and investigation of acid-base and electromigration properties of applied and potential peptide drugs by capillary electromigration methods.
Vaclav Kasicka - Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Electromigration methods - Prague, Czech Republic
|On-chip sample preparation using a ChipFilter coupled to nanoLC-MS/MS for bottom-up proteomics.
Ndiaye Massamba Mbacké - ESPCI Paris, Laboratoire de Spectrométrie de Masse Biologique et Protéomique SMBP - Paris, France
|11h25||Physicochemical protein properties, quality and binding affinities.
Hermann Wätzig - Medicinal and Pharmaceutical Chemistry, Technical University - Braunschweig, Germany
|Solid sampling probe based on a polymer inclusion membrane.
YS - Hui Yin Tey -University of Technology Malaysia, Centre for Sustainable and Nanomaterials - Johor, Malaysia
|11h40||Metabo-ring study: a multi-center trial for the identification of metabolites in biological samples by CE-MS.
YS - Nicolas Drouin - Leiden University, Analytical Biosciences and Metabolomics - Leiden, The Netherlands
|New approach for on-chip magnetic immuno-extraction of exosomes.
Monica Araya-Farias -Curie Institute, UMR 168 - Paris, France
|11h55||Selection and application of markers for CE-DAD migration time correction of peptide maps used to assess enzyme activity.
Karen Waldron - University of Montreal, Department of Chemistry - Montreal, Canada
|Buffer exchange using bidirectional flow.
YS - Vesna Bacheva - IBM Research - Zurich, Suisse
Technion - Israel Institute of Technology, Science and Technology department - Haifa, Israël
|12h15 - 13h00||Seminar|
|14h45||Portable and purpose-made devices
Chair: Peter Hauser
University of Basel, Basel, Switzerland
|Biomarkers; clinical, diagnostic and forensic applications
Chairs: Frederic Robert - Sebia, Lisses, France
Philip Britz-McKibbin - McMaster University, Hamilton, Canada
|14h50||KN 12 - A few contributions to the development of capillary electrophoresis systems
Claudimir Lucio do Lago
Institute of Chemistry, University of São Paulo, Brasil
|KN 13 - Capillary Electrophoresis application in Forensic Medicine and Science
Unit of Forensic Medicine, Department of Diagnostics
and Public Health, University of Verona, Verona, Italy
|15h15||A portable CE-LIF prototype system of the Ocean Worlds Life Surveyor (OWLS) instrument suite for potential astrobiology spaceflight missions.
Florian Kehl - NASA Jet Propulsion Laboratory, California Institute of Technology Chemical Analysis and Life Detection - Pasadena, USA
|In-depth characterization of glycated and carbamylated hemoglobin in clinical samples by top-down CE-MS/MS.
Alexander Stolz - Aalen University - Germany
|15h30||A microfluidic HPLC-droplet-ESI-MS chip for the investigation of enzyme inhibitors.
YS - Andrea Peretzki - Leipzig University, Institute of Analytical Chemistry - Leipzig, Germany
|Capillary Isotachophoresis separation of exosomes.
Yuliya Shakalisava - Leiden University, Leiden Academic Center for Drug Research - Leiden, The Netherlands
|15h45||Application of Microfluidic Glass-based Interfaces for 2D Electromigrative Separation Techniques.
YS - Hannes Graf - Eberhard Karls Universität Tübingen, Institute of Physical and Theoretical Chemistry - Tübingen, Germany
|Deep and highly sensitive CZE-MS-based glycan profiling of human plasma and blood-derived immunoglobulin G and extracellular vesicle isolates.
Alexander Ivanov - Northeastern University College of Science, Department of Chemistry and Chemical Biology - Boston, USA
|16h00||A new concept for modular CE with LiF detection: a highlight with O-glycans analysis.
YS - Théo Liénard--Mayor - Institut Galien Paris-Sud, PNAS - Chatenay-Malabry, France
|Steroid profile in human seminal fluid: is it linked to sperm quality?
YS - Eulalia Olesti - Biomedical and metabolomics analysis, Analytical Sciences, University of Geneva - Geneva, Switzerland
16h35 - 17h15
|New developments in metabolomics with CE-MS
Coral Barbas - Center for Metabolomics and Bioanalysis (CEMBIO) - Universidad San Pablo CEU - Madrid, Spain
|17h15 - 17h30||Awards/Prizes ceremony|
17h30 - 17h50
|Workshop: How to build an open-source capillary electrophoresis? Part 4|
|17h50 - 18h00||MSB 2021|
|18h00 - 18h15||Closing ceremony|